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Schematic representation of type I IFN signaling. Viruses and their antagonistic proteins are indicated at the steps of the IFN pathway they affect. Antagonistic proteins are shown adjacent to their targets in alphabetical order. Antagonists in red indicate proof for IFN antagonist by recombinant viruses lacking the IFN antagonist. Antagonists in blue indicate proof by over expression and/or wild-type virus infection.
