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Immunohistochemical staining of DNMT1 protein in pancreatic cancer. (A) Nuclear labeling of DNMT1 and (B) no DNMT1 labeling in the malignant tumor cells; (C) Expression of DNMT1 and (D) Lack of DNMT1 expression in normal ductal epithelial cells; (E) A “Histo-score” was generated as the product of intensity times area.
