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Accuracy of INR4 dose refinement algorithms in the validation cohorts.
| R2 | MAE (mg/day) [25%,75%] |
Predictions within 1 mg of therapeutic dose |
|
|---|---|---|---|
| Clinical Algorithm (N=146) |
48% | 0.74 [0.29,1.4] | 70% |
| Pharmacogenetic Algorithm (N=146) |
70% | 0.73 [0.31,1.29] | 73% |
MAE=Median Absolute Error. INR4 = International Normalized Ratio after the fourth warfarin dose.
