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. Author manuscript; available in PMC: 2011 Jul 22.
Published in final edited form as: J Med Chem. 2010 Jul 22;53(14):5197–5212. doi: 10.1021/jm100217a

Figure 4.

Figure 4

Effect of compounds 25-27 on the re-expression of secreted frizzle-related protein 2 (SFRP2, Panel A) and the transcription factor GATA4 (Panel B) mRNA. Calu-6 human anaplastic non-small cell lung carcinoma cells were treated with either a 5 or 10 μM concentration of 25, 26 or 27 for 24 hours as described in the methods section. cDNA was then synthesized from mRNA, amplified and measured by qPCR. Each data point is the average of 3 determinations that differed in all cases by 5% or less.