Table 1.

Structures of compounds 1c, 2d and 3-33, and inhibition of LSD1 in vitro following treatment with each analogue at 10 μM.

Compound	Compound	%LSD1 activity remaining
	1c	14.1 (from ref. 25)
	2d	17.2
	3	74.8
	4	49.5
	5	49.2
	6	40
	7	100
	8	79
	9	89.6
	10	35.9
	11	95.9
	12	91.5
	13	52.1
	14	65.5
	15	60.5
	16	51.3
	17	100
	18	36.2
	19	92.9
	20	92.2
	21	74.6
	22	88.6
	23	51.5
	24	77.3
	25	19.5
	26	17.1
	27	24.8
	28	51.1
	29	34.4
	30	28.9
	31	26.1
	32	70
	33	91.5