Table 4.

Associations of baseline HPV16 and HPV18 DNA load with status as a current smoker, stratified by race, parity, and coinfection with other HPV types

	Log10 HPV16 E7 copies per 1 nanogram of cellular DNA					Log10 HPV18 E7 copies per 1 nanogram of cellular DNA
	Never smokers		Current smokers			Never smokers		Current smokers
Characteristic	No.	Mean (SD)	No.	Mean (SD)	OR (95% CI)	No.	Mean (SD)	No.	Mean (SD)	OR (95% CI)
Overall	353	2.65 (1.36)	354	2.92 (1.34)	1.15 (1.02–1.30)*	161	3.73 (1.58)	119	4.13 (1.68)	1.23 (1.04–1.45)*
Race†
White	201	2.77 (1.28)	300	2.92 (1.34)	1.10 (0.96–1.26)	72	3.55 (1.61)	90	4.15 (1.66)	1.26 (1.03–1.53)
Nonwhite	151	2.48 (1.46)	51	2.96 (1.33)	1.29 (1.02–1.65)	89	3.89 (1.56)	28	4.05 (1.82)	1.07 (0.82–1.40)
Parity
Nulliparous	179	2.82 (1.27)	157	3.15 (1.23)	1.24 (1.04–1.47)	64	3.76 (1.45)	59	4.37 (1.44)	1.35 (1.04–1.75)
Parous	174	2.47 (1.43)	197	2.75 (1.41)	1.16 (1.00–1.34)	97	3.72 (1.67)	60	3.88 (1.87)	1.06 (0.88–1.27)
Referral Pap
ASC-US	224	2.53 (1.44)	205	2.82 (1.31)	1.17 (1.02–1.35)	74	3.52 (1.76)	64	3.82 (1.83)	1.10 (0.91–1.33)
LSIL	129	2.85 (1.18)	149	3.07 (1.37)	1.15 (0.95–1.38)	87	3.91 (1.41)	55	4.48 (1.42)	1.35 (1.04–1.74)
Current use of oral contraceptives
No	171	2.57 (1.44)	191	2.94 (1.41)	1.21 (1.04–1.41)	91	3.88 (1.64)	63	4.11 (1.87)	1.08 (0.89–1.30)
Yes	182	2.71 (1.29)	159	2.91 (1.26)	1.13 (0.95–1.34)	70	3.54 (1.50)	54	4.14 (1.45)	1.34 (1.03–1.73)
Coinfection with other HPV types
No	92	2.75 (1.28)	106	3.11 (1.33)	1.24 (1.00–1.55)	41	4.11 (1.52)	28	4.98 (1.56)	1.47 (1.03–2.09)
Yes	261	2.61(1.39)	248	2.85 (1.34)	1.14 (1.00–1.30)	120	3.60 (1.59)	91	3.86 (1.64)	1.11 (0.93–1.32)

^*Adjusted for age at enrollment, race, parity, referral Pap, current use of oral contraceptives, and coinfection with other HPV types

^†Excluded were 4 HPV16-positive women and one HPV18-positive woman who did not provide race information