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CD8+ T-pro defining genes are associated with progression to carcinoma
| WK12 tumors | WK16 papillomas | WK16 carcinomas |
|---|---|---|
| Upregulated (TIL/PBL >10) | RORγt | |
| IL-17A | IL-17A | |
| IL-17F | IL-17F | |
| IL-21 | ||
| IL-22 | ||
| FoxP3 | ||
| IL-10 | IL-10 | |
| Tim-3 | Tim-3 | Tim-3 |
| AREG | AREG | |
| Gro-1 | Gro-1 | |
| Gro-2 | Gro-2 | |
| NKG2D | ||
| Downregulated (TIL/PBL <0.1) | Tbet | |
| Eomes | ||
| Perforin | Perforin | Perforin |
| NKG7 | ||
| CCL5 | ||
