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. 2010 Aug 12;5(8):e12120. doi: 10.1371/journal.pone.0012120

Table 1. Screening of CD8 T cell lines enriched in HCMV- or EBV-specific T cells for cross-reactivity to allogeneic MHC molecules.

Donor# Molecular HLA class I typing % of tetramer-positive T cells Reactivity to allogeneic HLAa
HLA-A* HLA-B* HLA-Cw*
pp65/A*0201-sorted T cell lines
D01 0201 0301 3501 4402 0401 0501 97 A*3101
D02 0201 33 08 14 07 08 98 none
D03 0201 0201 1302 5101 0202 0602 99 A*3201
D04 0201 ND ND ND 98 none
D05 0201 ND ND ND 99 none
D06 0201 ND ND ND 99 none
D07 0201 2301 2705 4402 0102 0509 98 none
D08 0201 2301 4101 4402 0501 1701 89 A*3001
D09 0201 30 08 44 04 07 98 none
D10 0201 0201 1501 4403 0304 0501 95 none
D11 0201 1101 0801 2705 01 07 97 none
BMLF1/A*0201-sorted T cell lines
D12 0201 3201 15 15 0303 04 93 none
D13 0201 0201 2705 4002 0102 1501 95 none
BZLF1/B*3501-sorted T cell lines
D14 0301 1101 0701 3501 04 07 92 none
D15 2402 3101 3501 4001 03 07 97 Cw*0602
D16 2402 3201 2705 3501 01 04 97 none
a

CD8 T cell lines were screened on COS-7 cells transfected with individual HLA-encoding cDNA and TNF-α production was measured after a 6h-coculture. All T cell lines were PBL-derived. ND : not determined.