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. Author manuscript; available in PMC: 2010 Aug 12.
Published in final edited form as: Curr Opin Mol Ther. 2008 Dec;10(6):602–610.

Table 1.

Biotinylated lectins used for glycan detection and their specificities.

Biotinylated lectin Glycan structure detected
ConA α-Linked mannose
MAL Sialic acid in an (α-2,3) linkage
AAL Fucose linked (α-1,6) to N-acetylglucosamine or to Fucose linked (α-1,3) to N-acetyllactosamine
SNA Sialic acid attached to terminal galactose in (α-2,6), and to a lesser degree, (α-2,3), linkage
PNA Galactosyl (β-1,3) N-acetylgalactosamine

AAL aleuria aurantia, ConA, concanavalin A, MAL maackia amurensis II, PNA peanut agglutinin, SNA sambucus nigra (elderberry) bark.

(Reprinted with permission from Patwa TH, Zhao J, Anderson MA, Simeone DM, Lubman DM: Screening of glycosylation patterns in serum using natural glycoprotein microarrays and multi-lectin fluorescence detection. Anal Chem (2006) 78(18):6411-6421–2007 American Chemical Society) [19•].