Table 1.
The effect of inhibitors on Zn2+-induced H2O2 production.
| Inhibitora | Concentration (μM) | Percent inhibition |
|---|---|---|
| Apocynin | 100 | 21 |
| DPI | 25 | 7 |
| C56 | 10 | 3 |
| Wortmannin | 10 | 10 |
| Ly294002 | 10 | 0 |
| EHT 1864 | 5 | 5 |
| CCCP | 10 | 32* |
a
Cells incubated with inhibitors in various concentrations 30 min prior to 100 μM Zn2+ exposure. Inhibition effects were calculated by comparison of Zn2+-induced PG1 fluorescence after 30 min exposure with or without prior inhibitor treatment.
*
Denotes statistically significant difference from vehicle control, p < 0.05.