Table 1.
Characteristic | Number evaluated or evaluable | Median (range) |
---|---|---|
Age, years | 42 | 63 (44–81) |
Gender, male (%) | 42 | 21 (50) |
Durie Salmon II/III (%) | 37 | 16 (39)/21 (51) |
Durie Salmon A/B (%) | 41 | 34 (83)/7 (17) |
Isotype: IgG/IgA/Light chain only (%) | 38 | 25 (60)/7 (17)/6 (14) |
Hemoglobin, g/dL | 42 | 9.7 (7.6–15.3) |
Creatinine, mg/dL | 42 | 1.2 (0.6–3.8) |
Calcium, mg/dL | 42 | 8.8 (6.63–15.5) |
Serum M-spike, g/dL | 37 | 4.4 (1.4–8.8) |
Urine M-spike, g/day | 20 | 389 (10–4713) |
Bone marrow plasmacytosis | 50 (1,100) | |
Beta-2 microglobulin, mg/mL (range) | 42 | 7.7 (2.5–31.9) |
B2M ≥ 5.5 | 32 (76) | |
PCLI, % (range)§ | 33 | 1.6 (0 – 5) |
PCLI ≥ 1 | 17 (40) | |
Deletion 13q-*(%) | 41 | 6 (14) |
Translocation (4;14)(%) | 24 | 4 (10) |
Translocation (14;16)(%) | 24 | 0 (0) |
Deletion 17p (%) | 24 | 2 (5) |
By metaphase cytogenetics