Table 1.
Comparisons between sham, HSV-LacZ, and HSV-GAD groups in urodynamic parameters
Bladder contraction |
Urethral contraction |
||||
---|---|---|---|---|---|
Interval (min) | Amplitude (cm H2O) | Baseline pressure (cm H2O) | Urethral pressure change (cm H2O) | Baseline pressure (cm H2O) | |
Sham (n = 10) | 0.47 ± 0.07 | 26.0 ± 2.8 | 17.0 ± 1.3 | 17.2 ± 2.5 | 21.4 ± 3.1 |
HSV-LacZ (n = 8) | 0.34 ± 0.04 | 28.0± 3.9 | 14.7 ± 0.9 | 18.7± 1.9 | 13.2± 2.3 |
HSV-GAD (n =10) | 0.37 ± 0.03 | 21.6 ± 3.4 | 18.0 ± 1.4 | 4.0 ± 1.1**†† | 16.9 ± 4.1 |
Values are the mean ± SE. Significant differences when compared with sham are indicated by:
p < 0.01.
Significant differences when compared with HSV-LacZ are indicated by:
p < 0.01.
HSV, herpes simplex virus; GAD, glutamic acid decarboxylase