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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Arthritis Rheum. 2010 Aug;62(8):2525–2529. doi: 10.1002/art.27516

Table 2.

Recurrence risk of JIA among siblings and cousins of cases with JIA and matched controls.

Relative class Cases Controls RR (95% CI) P value
Relatives JIA Rate Relatives JIA Rate
Siblings 544 14 0.0257 3578 8 0.0022 11.6 (4.9–27.5) < 2.59 × 10−8
First cousins 1896 10 0.0053 10969 11 0.0010 5.82 (2.5–13.8) < 6.07 × 10−5
Second cousins 6348 8 0.0012 36247 44 0.0012 1.05 (0.5–2.23) 0.89
Total 8788 32 0.0038 50794 63 0.0012

The rate of JIA among relatives of cases was compared with the rate of JIA among relatives of controls to yield the recurrence risk of JIA among relatives of probands with JIA. Significant results are shown in bold. RR = recurrence risk.