Skip to main content
. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Eur J Cardiothorac Surg. 2010 May 10;38(6):691–698. doi: 10.1016/j.ejcts.2010.03.049

Figure 1.

Figure 1

Ligation of the distal LAD and D2 leads to a reproducible infarct in fetal and adult hearts. An anteroapical MI is created by ligating the LAD and D2 at a point 40% of the distance between the apex and the base in (a) fetal and (b) adult sheep. Activated caspase-3 staining of fetal hearts 3 days following infarction demonstrates (c) apoptosis in the area of infarction (400×) and (d) lack of apoptosis away from the area of infarction (400×). Scale bars equal 200µm.