Fig. 1.

Description of Full Outline of UnResponsivenes (FOUR) score. Eye response: E4 eyelids open or opened, tracking or blinking to command; E3 eyelids open but not tracking; E2 eyelids closed but open to loud voice; E1 eyelids closed but open to pain; E0 eyelids remain closed with pain. Motor response: M4 thumbs-up, fist or peace sign; M3 localising to pain; M2 flexion response to pain; M1 extension response to pain; M0 no response to pain or generalised myoclonus status. Brainstem reflexes: B4 pupil and corneal reflexes present; B3 one pupil wide and fixed; B2 pupil or corneal reflexes absent; B1 pupil and corneal reflexes absent; B0 absent pupil, corneal and cough reflex. Respiration pattern: R4 not intubated, regular breathing pattern; R3 not intubated, Cheyne-Stokes breathing pattern; R2 not intubated, irregular breathing; R1 breathes above ventilatory rate; R0 breathes at ventilator rate or apnea