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. 2010 Aug 14;16(30):3773–3779. doi: 10.3748/wjg.v16.i30.3773

Table 2.

Medical therapy vs surgery for Barrett’s esophagus n (%)

Publication Treatments PPI Nissen Progression PPI Progression Nissen Regression PPI Regression Nissen Study type
Gatenby et al[6], 2009 PPI vs Nissen 646 41 154 (24) 4 (10) NA NA Cohort
Parrilla et al[28], 2003 H2RA/PPI vs Nissen 43 58 10 (23) 5 (9) 2 (5) 5 (9) RCT
Rossi et al[29], 2006 PPI vs successful Nissen 19 16 NA NA 12 (63) 16 (100) Case comparison
Total 708 115 164 (23.8) 9 (9.1) 14 (22.6) 21 (28.4)

PPI: Proton pump inhibitor; H2RA: H2 receptor antagonist; RCT: Randomized controlled trial; NA: Not applicable.