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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Nature. 2010 Jul 1;466(7302):113–117. doi: 10.1038/nature09114

Figure 1. Manhattan plot of the joint analysis of the discovery GWAS and the replication GWAS.

Figure 1

Results are plotted as negative log-transformed P values from a genotypic association test controlled for residual population stratification as a function of the position in the genome. Odd chromosomes are in green and even chromosomes in blue. Eight genomic regions contain SNPs that exceed the genome-wide significance threshold of 5 × 10−7 (red line).