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. Author manuscript; available in PMC: 2010 Aug 13.
Published in final edited form as: J Immunol. 2008 Nov 15;181(10):7214–7220. doi: 10.4049/jimmunol.181.10.7214

FIGURE 3.

FIGURE 3

Blocking both IL-10 and TGF-β exacerbates hepatocellular damage and granulomatous pathology, but does not affect fibrosis. A, Liver granuloma cross-sectional area was determined 52 days postinoculation. 300 granulomas were measured per group. B, Serum levels of AST in naive or S. mansoni infected mice 52 days postinfection. C, Liver hydroxyproline levels 52 days postinfection. Means ± SE of six to eight mice/group. Experiments performed three times with similar results (*, p < 0.05; **, p < 0.01; and ***, p < 0.001 compared with isotype control-treated group).