Table 3. Univariate Analysis of Four-Year Ischemic Stroke Risk among 1,483 Elderly Anterior Myocardial Infarction Patients.
Variable | Stroke | Non-Stroke | P-value |
N = 118 | N = 1,365 | ||
Patient Demography | |||
Age at admission for MI | 76.77±6.69 | 76.52±6.97 | 0.71 |
Male gender | 58 (49.2%) | 756 (55.4%) | 0.19 |
Past Medical History | |||
Diabetes mellitus | 50 (42.4%) | 346 (25.3%) | <.001 |
Myocardial infarction | 33 (28.0%) | 319 (23.4%) | 0.26 |
Congestive heart failure | 8 (6.8%) | 92 (6.7%) | 0.99 |
Hypertension | 63 (53.4%) | 677 (49.6%) | 0.43 |
Previous smoker | 32 (27.1%) | 363 (26.6%) | 0.90 |
Previous atrial fibrillation | 2 (1.7%) | 16 (1.2%) | 0.62 |
Previous ischemic stroke | 4 (3.4%) | 22 (1.6%) | 0.16 |
In Hospital Findings & Procedures | |||
Killip class ≥3 | 6 (5.1%) | 51 (3.7%) | 0.47 |
LV dysfunction | 27 (22.9%) | 334 (24.5%) | 0.70 |
LV aneurysm, thrombus, or VSD | 6 (5.1%) | 67 (4.9%) | 0.93 |
Reperfusion therapy | 37 (31.4%) | 525 (38.5%) | 0.13 |
In-hospital onset of atrial fibrillation | 16 (13.6%) | 104 (7.6%) | 0.02 |
In-hospital onset of ischemic stroke | 0 (0.0%) | 5 (0.4%) | 0.51 |
Discharge systolic blood pressure | 126.11±25.59 | 120.47±20.31 | 0.006 |
Discharge diastolic blood pressure | 67.18±13.42 | 66.39±12.04 | 0.51 |
Discharge Medications | |||
ACE inhibitors | 62 (52.5%) | 868 (63.6%) | 0.017 |
ARB | 2 (1.7%) | 41 (3.0%) | 0.42 |
Antiarrhythmic therapy or digoxin | 26 (22.0%) | 239 (17.5%) | 0.22 |
Aspirin | 80 (67.8%) | 987 (72.3%) | 0.30 |
Beta-adrenergic antagonists | 62 (52.5%) | 868 (63.6%) | 0.02 |
Calcium antagonists | 35 (29.7%) | 335 (24.5%) | 0.22 |
Diuretics | 42 (35.6%) | 476 (34.9%) | 0.88 |
LMWH | 3 (2.5%) | 24 (1.8%) | 0.54 |
Nitrates | 53 (44.9%) | 580 (42.5%) | 0.61 |
Clopidogrel | 7 (5.9%) | 64 (4.7%) | 0.54 |
Statins | 29 (24.6%) | 372 (27.3%) | 0.53 |
Warfarin | 15 (12.7%) | 205 (15.0%) | 0.50 |
Drug Benefit Claims for Warfarin | |||
Within 30-days post discharge | 11 (9.3%) | 185 (13.6%) | 0.19 |
Within 90-days post discharge | 12 (10.2%) | 191 (14.0%) | 0.25 |
Data are reported as number (percentage) of patients or mean ± standard deviation (SD) value unless otherwise specified.