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. 2010 Aug 13;5(8):e12150. doi: 10.1371/journal.pone.0012150

Table 3. Univariate Analysis of Four-Year Ischemic Stroke Risk among 1,483 Elderly Anterior Myocardial Infarction Patients.

Variable Stroke Non-Stroke P-value
N = 118 N = 1,365
Patient Demography
Age at admission for MI 76.77±6.69 76.52±6.97 0.71
Male gender 58 (49.2%) 756 (55.4%) 0.19
Past Medical History
Diabetes mellitus 50 (42.4%) 346 (25.3%) <.001
Myocardial infarction 33 (28.0%) 319 (23.4%) 0.26
Congestive heart failure 8 (6.8%) 92 (6.7%) 0.99
Hypertension 63 (53.4%) 677 (49.6%) 0.43
Previous smoker 32 (27.1%) 363 (26.6%) 0.90
Previous atrial fibrillation 2 (1.7%) 16 (1.2%) 0.62
Previous ischemic stroke 4 (3.4%) 22 (1.6%) 0.16
In Hospital Findings & Procedures
Killip class ≥3 6 (5.1%) 51 (3.7%) 0.47
LV dysfunction 27 (22.9%) 334 (24.5%) 0.70
LV aneurysm, thrombus, or VSD 6 (5.1%) 67 (4.9%) 0.93
Reperfusion therapy 37 (31.4%) 525 (38.5%) 0.13
In-hospital onset of atrial fibrillation 16 (13.6%) 104 (7.6%) 0.02
In-hospital onset of ischemic stroke 0 (0.0%) 5 (0.4%) 0.51
Discharge systolic blood pressure 126.11±25.59 120.47±20.31 0.006
Discharge diastolic blood pressure 67.18±13.42 66.39±12.04 0.51
Discharge Medications
ACE inhibitors 62 (52.5%) 868 (63.6%) 0.017
ARB 2 (1.7%) 41 (3.0%) 0.42
Antiarrhythmic therapy or digoxin 26 (22.0%) 239 (17.5%) 0.22
Aspirin 80 (67.8%) 987 (72.3%) 0.30
Beta-adrenergic antagonists 62 (52.5%) 868 (63.6%) 0.02
Calcium antagonists 35 (29.7%) 335 (24.5%) 0.22
Diuretics 42 (35.6%) 476 (34.9%) 0.88
LMWH 3 (2.5%) 24 (1.8%) 0.54
Nitrates 53 (44.9%) 580 (42.5%) 0.61
Clopidogrel 7 (5.9%) 64 (4.7%) 0.54
Statins 29 (24.6%) 372 (27.3%) 0.53
Warfarin 15 (12.7%) 205 (15.0%) 0.50
Drug Benefit Claims for Warfarin
Within 30-days post discharge 11 (9.3%) 185 (13.6%) 0.19
Within 90-days post discharge 12 (10.2%) 191 (14.0%) 0.25

Data are reported as number (percentage) of patients or mean ± standard deviation (SD) value unless otherwise specified.