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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: J Med Primatol. 2010 Aug;39(4):194–212. doi: 10.1111/j.1600-0684.2010.00432.x

Figure 8. Co-evolution between MHC class I genes and KIR in primates.

Figure 8

Shows the distribution in non-human primates of genes orthologous to human HLA-A, B, C, E, and G. The species distribution of the Bw/Bw6 epitopes and the C1/C2 epitopes distinguished by KIR is also shown. Few gorilla MHC-C alleles have been defined and they all have the C2 epitope. Thus C1 may have been lost from gorilla. Under ‘KIR’ are described the changes in the KIR locus that accompany the changes in MHC class I. For each species the time since the last common ancestor with humans is given.

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