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. 2010 Aug 13;5(8):e12190. doi: 10.1371/journal.pone.0012190

Table 1. Functional annotation of the sex-independent cluster.

Ontology Keywords P-value
Acute phase response (ES : 4.3–25 genes)SAA1, SAA2, SAA3, SAA4, ORM3, SERPINA3N, C8a, C9
SP_PIR_KEYWORDS Acute phase 2.9×10−6
GO_BP Acute-phase response 6.4×10−6
GO_BP Acute inflammatory response 1.8×10−5
INTERPRO Serum amyloid A protein 8.6×10−5
SMART SAA 6.1×10−6
Lipid metabolism (ES : 3.9–38 genes)CRAT, ACOX1, ACOT2, ACOT5, EHHADH, ACAA1A, CPT1B, PLTP
GO_BP Fatty acid metabolic process 1.3×10−7
GO_BP Monocarboxylic acid metabolic process 9.1×10−9
SP_PIR_KEYWORDS Fatty acid metabolism 8.4×10−6
BO_BP Lipid metabolic process 1.6×10−9
GO_CC Peroxysome 3.3×10−5
GO_CC Microbody 3.3×10−5
Steroid metabolic process (ES : 3.3–14 genes)STAR, IDI1, MOGAT1, LEPR, FABP5, PCTP, AKR1C18, FBP2, HMGCS1
GO_BP Steroid metabolic process 1.7×10−4
GO_BP Alcohol metabolic process 5.5×10−4
GO_BP Cholesterol metabolic process 6.8×10−4
GO_BP Sterol metabolic process 1.0×10−3
Thrombospondin (ES : 1.8–5 genes)SPON2, C9, SEMA5B, ADAMTS20, C8A
SMART TSP1 1.7×10−3
INTERPRO Thrombospondin, type I 1.9×10−3

The enrichment score (ES), the number of genes and example genes in each group of genes were indicated.