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(a) Madajet (pneumatic jet device) used for noninvasive delivery of small quantities of the OCA through the skin. (Reproduced with permission from Pfenninger Medical Procedures Center P.C., John L. Pfenninger, M.D.). (b) Pattern for delivering the OCA on the treatment site. Four injections were spaced equally around the 3-mm-diam laser spot, and then the OCA was allowed to diffuse into the laser treatment area over time.
