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. Author manuscript; available in PMC: 2010 Aug 13.
Published in final edited form as: J Immunol. 2009 Nov 30;184(1):84–93. doi: 10.4049/jimmunol.0901590

FIGURE 7.

FIGURE 7

The immediate-phase PCA response in WeeB mice is stronger than the response in wt or lyn−/− mice. A, IgE serum levels of 10-to 12-wk-old mice were measured by ELISA. B, PCA reactions were measured as described in the Materials and Methods. Results are expressed as the mean ± SEM. C, Dermal mast cell numbers in IgE-sensitized and PBS (vehicle)-treated ears after Ag challenge were obtained by staining with toluidine blue. Cells with metachromatically stained granules were counted as mast cells. D, The percentage of degranulated mast cells was determined morphologically. Degranulated mast cells were not observed in PBS-treated ears. E, PCA reactions in C57BL/6-KitW-sh/W-sh mice were performed as in B. *p <0.05; **p <0.001. Error bars represent SEM. Significance was determined by ANOVA.