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. Author manuscript; available in PMC: 2011 Sep 15.
Published in final edited form as: Free Radic Biol Med. 2010 Jun 8;49(6):976–983. doi: 10.1016/j.freeradbiomed.2010.05.030

Figure 2. Sag disruption sensitizes ES cells to radiation-induced apoptosis.

Figure 2

ES cells with genotype of Sag+/+ and Sag−/− were left untreated or exposed to 10 Gy radiation, followed by DNA fragmentation assay 24 hrs later (A), Western blotting for PARP cleavage at indicated time points (B), or ELISA assay for caspase-3 activity, 24 hrs post radiation (C).