Table 4.
Significant Connectivity Differences for IPV-PTSD vs. Controls for Matching to a Fearful vs. Happy Target Face
| Voxelwise Statistics: Mean (S.D.) | ||||||||
|---|---|---|---|---|---|---|---|---|
| Seed ROI | Side | Connection ROI | Size(μl) | X | Y | Z | F* | p* |
| Dorsal ACC | R | Insula (p) | 384 | 38 | -28.3 | 17.4 | 6.250 (1.94) | .016 (.006) |
| L | Insula (a)(-) | 320 | -41.9 | 11 | 12 | 9.064 (1.74) | .008 (.005) | |
| Left Insula (a) | L | Amygdala (-) | 448 | -18.6 | -5 | -16.5 | 6.760 (3.07) | .035 (.017) |
| L | Insula (a)(-) | 448 | -42.3 | 9.9 | 12.6 | 10.256 (3.06) | .007 (.005) | |
| Left Insula (a) | L | Insula (a)(-) | 640 | -35.5 | 13.9 | -5.8 | 11.233 (5.21) | .013 (.022) |
| L | Insula (a/m)(-) | 640 | -41.8 | 10.1 | 11.2 | 5.992 (2.03) | .035 (.027) | |
| R | Insula (p)(-) | 512 | 41.4 | -12.4 | 4.9 | 7.017 (3.03) | .025 (.020) | |
| R | Amygdala (-) | 320 | 26.7 | -7.4 | -15.2 | 5.170 (1.75) | .047 (.030) | |
| R | Insula (m)(-) | 320 | 41.1 | -14.1 | -8 | 5.640 (0.68) | .028 (.008) | |
| L | Amygdala (-) | 192 | -24.7 | -2.1 | -12 | 6.016 (.797) | .024 (.008) | |
| Right Amygdala | L | Insula (a/m)(-) | 1472 | -36.1 | -1.3 | 10.3 | 6.248 (3.26) | .040 (.035) |
| B | Subgenual ACC | 1088 | -1.5 | 14.8 | -8.9 | 6.616 (2.74) | .033 (.037) | |
Cluster coordinates and anatomical areas are for cluster center of mass as defined by Talairach stereotactic space; Negative (-) signs following anatomical area indicate reduced connectivity; Descriptors for ACC and insula clusters do not reflect stereotactic distinctions, but are estimates based upon the relative location of activation on the group map;
*
Voxelwise statistics are presented with education covaried out; ROI=region of interest; WB=whole brain; m=middle insula; a=anterior insula; p=posterior insula.