Fig. 1.

Laminin-111 is found in the very early mouse embryo, here shown at day 6, even before a proper BM has assembled (a) and in BM remnants of migrating mesodermal cells (b) at day 7. M Mesodermal cell, N nucleus, S mesodermal space, EC ectodermal cell. (Taken from [200], with permission from the publisher). In adult murine kidney, the tail (formerly the E8 domain) of laminin-111 is orientated towards the lamina fibroreticularis in the basement membrane of the proximal tubule (c), while the molecule is randomly distributed in the distal tubule (d). C Cell, BM basement membrane. (Taken from [44], with permission from the publisher)