Figure 3. Clusters of human proximal promoters based on their repetitive DNA sequence distributions.
Proximal promoter sequences are represented left-to-right from position -1,000bp upstream to the transcriptional start site (TSS). Promoter sequences are color coded according to their repeat element distributions. Individual promoter nucleotide positions occupied by TEs are shown in blue, SSR positions are shown in yellow and non-repetitive positions are shown in black. The vertical size of the clusters corresponds to the number of sequences in each cluster. There are two (c1 & c2) clusters that contain promoters largely devoid of TE sequences (TE−), and the promoter sequences of the remaining four clusters (TE+, c3 — c6) contain increasing numbers of TEs.