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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Lab Invest. 2010 May 10;90(9):1325–1338. doi: 10.1038/labinvest.2010.99

Figure 2.

Figure 2

Co-treatment of cholangiocarcinoma cells with resveratrol and chemotherapeutic agents increases the incidence of cell death in vitro. Cholangiocarcinoma cells (Mz-ChA-1, SG231, CCLP-1 and HuCCT-1) were treated with resveratrol (Resv; 20 μM) prior to the addition of 5-FU (30 μM; A), Mitomycin C (Mito C; 5 μM; B), or Gemcitabine (Gemc; 30 μM; C) for 24hr. Apoptosis was assessed by Annexin V staining. Data are expressed as a percentage of Annexin V-positive cells per field (average ± SEM, of 10 non-overlapping fields). The * denotes significance (p<0.05) compared to basal, and the # denotes significance (p<0.05) compared to the chemotherapy treatment alone.