Table 1.
Hematological Assessment of HairlessSKH1/SKH1 Mice. Six mice (3 males and 3 females) ages 160–200 days were evaluated per strain. Statistical approaches are described in the methods section. Values in bold indicate indices exhibiting significant differences between C57Bl/6 and Hairless mice.
| C57Bl/6 | HairlessSKH1/SKH1 | ||||
|---|---|---|---|---|---|
| Mean | Std Dev | Mean | Std Dev | P value | |
| White blood cell count (×103 cells/μl) | 5.04 | 1.84 | 7.04 | 1.28 | 0.15 |
| Lymphocyte count (×103 cells/μl) | 4.25 | 1.71 | 4.94 | 1.08 | 0.52 |
| Monocyte count (×103 cells/μl) | 0.11 | 0.07 | 0.27 | 0.17 | 0.11 |
| (% lymphocytes) | 83.20 | 5.22 | 70.12 | 9.47 | 0.05 |
| (% of monocytes) | 2.03 | 1.20 | 3.97 | 2.76 | 0.3 |
| Red blood cell count (×103 cells/μl) | 10.89 | 0.34 | 10.48 | 0.38 | 0.08 |
| Hematocrit | 40.63 | 1.92 | 43.73 | 1.84 | 0.02 |
| Mean corpuscular volume (fL) | 37.33 | 1.21 | 41.83 | 1.83 | 0.004 |
| Mean corpuscular hemoglobin (pg) | 14.20 | 0.54 | 15.75 | 0.63 | 0.005 |
| Mean corpuscular hemoglobin concentration(g/dL) | 38.03 | 1.00 | 37.73 | 1.16 | 1 |
| Red blood cell distribution width (%) | 20.32 | 0.52 | 17.83 | 1.01 | 0.004 |
| Platelet (×103 cells/μl) | 414.00 | 117.13 | 594.83 | 277.83 | 0.26 |
| Mean platelet volume (fL) | 6.08 | 0.12 | 6.27 | 0.26 | 0.25 |