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. Author manuscript; available in PMC: 2011 Jun 1.
Published in final edited form as: Curr Opin Struct Biol. 2010 Jun;20(3):342–350. doi: 10.1016/j.sbi.2010.03.006

Figure 2. Allele frequency distribution.

Figure 2

The figure shows the derived allele frequency distribution for the three groups of polymorphisms from dbSNP database: 6337 coding synonymous SNPs (light yellow), 4687 non-synonymous SNPs predicted as benign by PolyPhen-2 (green), and 1301 non-synonymous SNPs predicted damaging by PolyPhen-2 (orange). The frequencies were measured in HAPMAP-YRI population (120 individuals).