Table 1.
Method Name | Description | URL |
---|---|---|
Align-GVGD [6,7] |
Phylogenetic method using phyisco- chemical amino acid properties |
http://agvgd.iarc.fr/agvgd_input.php |
LRT [9] | Phylogenetic method using estimated rate of evolution |
(no server) |
LS-SNP [40] | Database of polymorphisms, classified by phylogenetic and structural features combined with machine learning |
http://modbase.compbio.ucsf.edu/LS-SNP/ |
MAPP [5] | Phylogenetic method using patterns of physico-chemical properties of amino acid substitutions |
http://mendel.stanford.edu/sidowlab/downloads/MAPP/index.html |
MSRV [42.73] | Various phylogenetic methods combined with a custom machine learning algorithm |
http://bioinfo.steadybj.com/msrv |
nsSNPAnalyzer [74] |
Phylogenetic and structural features combined with machine learning |
http://snpanalyzer.utmem.edu/ |
PANTHER [75,76] |
Database of polymorphisms, classified by a phylogenetic method using patterns of amino acid substitutions |
http://www.pantherdb.org/tools/csnpScoreForm.jsp |
PhD-SNP [41] | Phylogenetic method using patterns of amino acid substitutions |
http://gpcr2.biocomp.unibo.it/cgi/predictors/PhD-SNP/PhDSNP.cgi |
PMut [8] | Phylogenetic and structural features combined with machine learning |
http://mmb2.pcb.ub.es:8080/PMut/ |
PolyPhen-2 [10] | Phylogenetic and structural features combined with machine learning |
http://genetics.bwh.harvard.edu/pph2 |
SIFT [3,4,77] | Phylogenetic method using patterns of amino acid substitutions |
http://sift.jcvi.org/ |
SNAP [11] | Phylogenetic and structural features combined with machine learning |
http://cubic.bioc.columbia.edu/services/SNAP/ |
SNPs3D [20,39,78] |
Combination of 2 methods, one phylogenetic and one based on structural features |
http://www.snps3d.org/ |
TopoSNP [38] | Database of polymorphisms, classified by structural features |
http://gila.bioengr.uic.edu/snp/toposnp/ |