Table 3.
Hazard Ratios Detected with Approximately 90% Power by Event Rate and Lowto-High Risk Group Ratio
| 3.a Analyses Based on the Total HCHS/SOL Sample (n = 16,000) | |||
|---|---|---|---|
| Ratio of low-risk to high-risk | |||
| Rate in low-risk group | 1:1 | 3:1 | 15:1 |
| 2/1000 person-years | 1.85 | 1.90 | 2.50 |
| 4/1000 person-years | 1.60 | 1.65 | 2.10 |
| 6/1000 person-years | 1.45 | 1.50 | 1.90 |
| 8/1000 person-years | 1.40 | 1.45 | 1.75 |
| 3.b Field Center- or Subgroup-Specific Analyses (n = 4,000) | |||
|---|---|---|---|
| Ratio of low-risk to high-risk | |||
| Rate in low-risk group | 1:1 | 3:1 | 15:1 |
| 2/1000 person-years | 2.95 | 2.95 | 4.15 |
| 4/1000 person-years | 2.25 | 2.35 | 3.20 |
| 6/1000 person-years | 2.00 | 2.05 | 2.80 |
| 8/1000 person-years | 1.85 | 1.90 | 2.55 |
| 10/1000 person-years | 1.75 | 1.80 | 2.40 |
Assuming 3-year accrual and 2-year follow-up periods and a design effect due to clustering of 1.25.
Assuming 3-year accrual and 2-year follow-up periods and a design effect due to clustering of 1.25.