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. Author manuscript; available in PMC: 2011 Sep 15.
Published in final edited form as: Anal Biochem. 2010 Jun 2;404(2):186–192. doi: 10.1016/j.ab.2010.05.033

Scheme I.

Scheme I

The rapid equilibrium random mechanism of the LRRK2-catalyzed PLK-peptide phosphorylation. A represents ATP and B represents PLK-peptide.