Table 2.
Selected characteristics and survival of 2,118 MDS patients diagnosed during 2001–2002 and included in SEER-medicare (unadjusted analyses)
| Characteristic | Hazard ratio | 95% CI | p for trend |
|---|---|---|---|
| Socioeconomic status | |||
| High | 1.00 | ||
| Medium | 1.18 | 1.04–1.33 | |
| Low | 1.26 | 1.10–1.43 | <0.01 |
| Gender | |||
| Female | 1.00 | ||
| Male | 1.15 | 1.04–1.28 | |
| Race | |||
| White | 1.00 | ||
| Black | 0.89 | 0.71–1.11 | |
| Other | 1.03 | 0.78–1.36 | |
| Age (years) | |||
| 66–69 | 1.00 | ||
| 70–74 | 1.11 | 0.90–1.38 | |
| 75–79 | 1.22 | 0.99–1.50 | |
| 80–84 | 1.38 | 1.13–1.70 | |
| 85+ | 1.93 | 1.57–2.38 | <0.01 |
| Charlson index | |||
| 0 | 1.00 | ||
| 1–2 | 1.19 | 1.06–1.33 | |
| 3+ | 1.76 | 1.52–2.03 | <0.01 |
| Subtypea (ICD-O-3 Code) | |||
| RA (9980) | 1.00 | ||
| RARS (9982) | 0.71 | 0.57–0.88 | |
| RAEB (9983) | 2.22 | 1.86–2.66 | |
| RAEB-t (9984) | 2.79 | 1.93–4.04 | |
| RCMD (9985) | 0.92 | 0.64–1.32 | |
| MDS with 5q deletion (9986) | 1.06 | 0.70–1.61 | |
| Therapy-related MDS (9987) | 1.32 | 0.87–2.00 | |
| MDS, not otherwise specified (9989) | 1.25 | 1.08–1.45 | |
a
RA refractory anemia, RARS RA with ringed sideroblasts, RAEB RA with excess blasts, RAEB-t RAEB in transformation, RCMD refractory cytopenia with multilineage dysplasia