Figure 1.

Diagram showing the experimental protocols studied by independently manipulating p_aO₂ and/or MABP (arrows) over time, including saline volume and time controls, hypotension ± hyperoxia and hypoxia ± hypertension, hyperoxia alone, hypertension alone, and hypoxic hypotension. The number of rats studied in each protocol is shown in parenthesis. The eight experimental conditions during that SDs were tested include (A) normoxic normotension (n=47 SDs); (B) normoxic hypotension (n=15 SDs); (C) hyperoxic hypotension (n=16 SDs); (D) hypoxic normotension (n=5 SDs); (E) hypoxic hypertension (n=5 SDs); (F) hyperoxic normotension (n=9 SDs); (G) normoxic hypertension (n=8 SDs); (H) hypoxic hypotension (n=4 SDs). The MABP and p_aO₂ values for each group are given in Figure 3.