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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Biochemistry. 2010 Aug 3;49(30):6341–6351. doi: 10.1021/bi100660r

Table 2.

Specificity of small molecules binding to SL1-related RNA constructsa

RNA KA-AMC R-AMC RR-AMC R-MHQ
SL1-fl KD 6.3 15.8 33.0 28.1
SL1-s KD 2.4 6.5 11.8 16.7
SL1-gril 5.8 6.7 18.3 13.9
a

Defined as the ratio of the apparent Kd for the binding to duplex RNA and apparent Kd for the binding to SL1-related RNA construct (Table 1).