Table 3.
Systolic and diastolic function variables (mean±s.d.) by echocardiography and Doppler tissue imaging at baseline and follow-up. The values are mean±s.d.
PHPT cases | P | ||||
---|---|---|---|---|---|
Variable | Controls n=51 | Baseline n=51 (35 females) | Follow-up n=50 (34 females) | PHPT baseline versus controls | PHPT baseline versus follow-up |
Systolic variable | |||||
DTI-RV systolic velocity (cm/s) (13.5±1.7)a | 13.85±1.77 | 14.23±1.85 | 13.48±1.79 | NS | <0.05 |
DTI-IVS systolic velocity (cm/s) (7.7±1.7)b | 8.23±1.00 | 8.48±0.96 | 7.97±0.85 | NS | <0.05 |
DTI-LVL systolic velocity (cm/s) (8.5±2.2)b | 9.80±1.89 | 9.61±2.05 | 8.87±1.63* | NS | <0.05 |
Ejection fraction (%) | 65.29±6.17c | 66.18±5.78c | 65.75±4.84c | NS | NS |
Fractional shortening (%) | 36.29±5.14c | 37.02±4.33c | 36.46±3.81c | NS | NS |
AV-plane RV (cm) | 2.64±0.32 | 2.58±0.37 | 2.50±0.39 | NS | NS |
AV-plane IVS (cm) | 1.44±0.20 | 1.42±0.18 | 1.39±0.19 | NS | NS |
AV-plane LV (cm) | 1.57±0.21 | 1.55±0.18 | 1.55±0.18 | NS | NS |
Diastolic variable | |||||
E-wave (cm/s) | 80.18±14.44 | 75.76±15.09 | 75.77±13.47 | NS | NS |
A-wave (cm/s) | 59.59±12.48 | 60.58±15.27 | 61.41±12.70 | NS | NS |
E/A | 1.39±0.33 | 1.30±0.34 | 1.27±0.28 | NS | NS |
DT (ms) | 197.9±22.6 | 199.7±27.9 | 200.8±29.3 | NS | NS |
Isovolumic relaxation time (ms) | 82.36±16.20 | 86.67±18.42 | 86.32±19.42 | NS | NS |
PVs/PVd | 1.16±0.27 | 1.22±0.34 | 1.21±0.32 | NS | NS |
E/E′ Septal | 7.81±1.73 | 7.69±1.74 | 7.54±1.58 | NS | NS |
E/E′ Lateral | 6.38±1.43 | 6.35±1.84 | 6.50±1.61 | NS | NS |
DTI, Doppler tissue imaging; AV-plane, atrioventricular plane displacement; RV, right ventricular wall; LVL, left ventricular lateral wall; IVS, interventricular septum; E-wave, early transmitral diastolic flow velocity; A-wave, flow velocity during atrial contraction; DT, deceleration time; PVs, systolic pulmonary vein velocity; PVd, diastolic pulmonary vein velocity; E/E′, a ratio of early transmitral diastolic flow velocity (E) and early diastolic velocity recorded by DTI (E′) in the mitral annulus. *The peak systolic velocity in the lateral part of the mitral annulus was lower in patients after PTX compared to controls, P<0.05.
Indicates the reference for published DTI values for RV (22).
Indicates the reference for published DTI values for LV (23).
n=49–50.