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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: J Am Chem Soc. 2010 Aug 4;132(30):10445–10452. doi: 10.1021/ja103166y

Table 1.

Effect of macromolecular crowding on folding energetics of P85A CRABP Ia

20° C 37° C

Ficoll 70 (g·l−1) m-value (cal·mol-1·M−1) Cm (M) ΔG° (cal·mol−1) m-value (cal·mol-1·M−1) Cm (M) ΔG° (cal·mol−1)
0 1568 ± 109 5.36 ± 0.02 8401 ± 580 1698 ± 127 4.27 ± 0.02 7252 ± 537
75 1448 ± 143 5.61 ± 0.03 8123 ± 791 1551 ± 92 4.48 ± 0.02 6951 ± 412
150 1326 ± 118 5.99 ± 0.04 7942 ± 681 1477 ± 90 4.81 ± 0.02 7100 ± 431
a

The parameter values plus the standard errors at each condition are the result of a global fitting of independent measurements (three to four data sets in general, and six for 37 °C/150 g/l Ficoll).