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. Author manuscript; available in PMC: 2010 Aug 16.
Published in final edited form as: Diabetes. 2007 Mar 30;56(7):1792–1801. doi: 10.2337/db06-1513

FIG. 7.

FIG. 7

Glucose infusion increases cyclin D2 abundance and nuclear localization. A: Islets from mice infused with saline or glucose for 4 days show that cyclin D2 protein abundance significantly increases; cyclin D1, cyclin D3, and cdk4 are unchanged. B: Immunohistochemistry for cyclin D2 reveals pronounced nuclear localization in islets from glucose-infused mice. C: Real-time PCR demonstrates no difference in mRNA abundance of D-type cyclins and cdks 4 and 6 in islets from saline- or glucose-infused mice. Scale bars = 20 μm (10 μm in insets). Data are means ± SE.