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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Arthritis Rheum. 2010 Aug;62(8):2206–2218. doi: 10.1002/art.27528

Table 1.

Gene and protein expression patterns in OA cartilage cell clusters.

Receptors, Kinases,
Transcription factors
Sox9(73,138)
Runx2(122)
C-maf (99)
Leptin/ Leptin receptor (28)
c-Fos,c-Jun(AP-1)(30)
HMGB1 (100)
Cytokines,
Growth factors
BMP-7(OP-1)(101)
FGF2(102)
BMP-2,−4,−6(103)
PGE2, COX-1,−2(104)
Histamine (105)
S-100(106)
IL-1β,TNFa(107)
Pleiotrophin(123)
WISP3 (110)
ECM,
ECM-degrading
Enzymes
Aggrecan (72,73)
Procollagen (64)
Col I (72)
Col II (64, 69, 72, 73)
Col VI (23)
Col X (120)
TIHP-1 (54)
5ZP(12)
MMP-1,−8,−13(107)
MMP-2, −3, −8,−9(108)
ADAMTS-10(109)
Cathepsin K (113), D (114), B (115)
Suits (116)
Syndecan-4(116)
Cell Death Apoptosis (103,111)
Autophagy (111, 112)
Progenitor Cell
Markers
Notch-1 (118,138)
Stro-1 (138, 116, 141)
VCAM-1 (138)
Ann ex in VI (42)
Plelotrophln(123)
HHS Vulnerability Disclosure