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. Author manuscript; available in PMC: 2010 Aug 16.
Published in final edited form as: J Am Chem Soc. 2008 Jun 13;130(27):8602–8603. doi: 10.1021/ja803139k

Table 1.

One-Pot Synthesis of Highly Functionalized Pyridines

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Uniform conditions unless otherwise noted: 2 eq diazo compound, 2 mol% Rh2(OAc)4, 30 min diazo compound addition at 60 °C, then reflux for 4 h, then rt DDQ addition

a

0.5 mol% Rh2(OAc)4 used

b

4 eq of diazo compound used

c

diazo compound added at reflux

d

3 eq of diazo compound used

e

refluxed overnight after diazo compound addition