Figure 2. PAF-AH activity in plasma and intestinal tissues of wild-type and PAF-AH−/− mice.
PAF-AH activity was determined as the rate of [3H] acetate released from 1-O-hexadecyl-[3H-acetyl]-PAF and expressed as nmol/min/mg. (A). Box-and-Whisker plot showing median serum PAF-AH activity in wild-type mice during development. The levels of PAF-AH activity in adult mouse and human serum samples are shown for comparison. * represents P < 0.01. (B). Gut PAF-AH activity in adult and neonatal wild-type (black bars) and PAF-AH−/− mice (white bars).
*p < 0.0001, age effect,
**p < 0.0001, genotype effect.