Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
a,b) Palmoplantar keratoderma affecting mainly the pressure regions in a man with PLS. c) Prominent tooth loss secondary to gingivitis occurring at 14 years of age. d) A deletion mutation designated c.21delG (p.Leu7PhefsX57) in the CTSC gene in the affected individual. The deleted nucleotide is boxed.
