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Effect of PLAD proteins on kidney pathology in MRL/lpr mice. MRL/lpr mice were treated with P60 PLAD (n= 8, 100 µg/mouse, three times a week, i.p.) or P80 PLAD protein (n= 8, 100 µg/mouse, three times a week, i.p.) or PBS (n= 8, 100 µl/mouse, three times a week, i.p.) starting at age of 6 weeks for 26 weeks. (A) Proteinuria from MRL/lpr mice treated with PBS or P60 or P80 PLAD protein. (B) Representative images of H&E stained tissue sections of kidney.
