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. Author manuscript; available in PMC: 2011 Jul 19.
Published in final edited form as: Inorg Chem. 2010 Jul 19;49(14):6338–6348. doi: 10.1021/ic9022757

Figure 3.

Figure 3

Visualization of fluorescence enhancement by CuFL1 in J774A.1 infected macrophages at 2 and 18 h post-infection. Top row: bNOS-expressing B. anthracis (Sterne) cells taken up by macrophages. Sterne cells produce NO using bNOS within 2 h of uptake. The host macrophages produce NO using iNOS between 2 and 18 h. Middle row: bNOS-deficient B. anthracis cells taken up by macrophages. No fluorescence is observed after 2 h because these bacteria cannot generate NO. The host macrophages produce NO using iNOS as usual. Bottom row: Control, no bacteria and no induction of iNOS