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. Author manuscript; available in PMC: 2011 Aug 1.
Published in final edited form as: Curr Opin Microbiol. 2010 Jun 2;13(4):431–436. doi: 10.1016/j.mib.2010.04.008

Table 1.

Selected examples of chromatin-level control affecting aspects of fungal development

Developmental aspect: Organism: Phenotypic Description: Reference:
Nitrate and Proline utilization Aspergillus nidulans
  • Nitrate and proline genes are clustered

  • Inducing/repressive conditions alter nucleosome positioning in promoter and histone H3 acetylation patterns

[50,51].

Adhesion Candida glabrata
  • Adhesins important pathogenicity factors in C. glabrata

  • Adhesins are produced by telomerically located EPA genes

  • EPA genes regulated by TPE and HDAC's

[52]

Growth and Reproduction Defects Neurospora crassa
  • Severe growth defects in null mutants of the H3K9 methyltransferase and heterochromatin protein 1.

[53,54]
Aspergillus fumigatus
  • Null mutant of H3K9 methyltransferase shows impaired growth and delayed asexual development

[55]
HHS Vulnerability Disclosure