Skip to main content
. Author manuscript; available in PMC: 2011 Jul 1.
Published in final edited form as: Cancer J. 2010 Jul–Aug;16(4):382–391. doi: 10.1097/PPO.0b013e3181eaca65

Figure 2. Major DC subsets in blood.

Figure 2

There are two subsets in blood, the myeloid DC (mDC) or the plasmacytoid DC (pDC). They are distinguished by surface marker expression, TLR expression, cytokine production and primary functional roles. It is now appreciated that pDC can also participate in the induction of adaptive immune responses although their precise roles need to be determined. While pDC do not synthesize IL-12, mDC can produce type I IFN via TLR3 ligation.