Figure 3.

Effect of IL-13 on oxytocin-evoked cytosolic free Ca²⁺ concentration ([Ca²⁺]_i). IL-13 (50 ng/ml) was pre-incubated for 24 hr before cells were exposed to 100 nM oxytocin. (A) Typical Ca²⁺ traces from cells incubated in the absence or presence of IL- 13. (B) Graphical representation of values for the Ca²⁺ peak phase from cells incubated in the absence or presence of IL-13. Results are expressed as the net increase in [Ca²⁺]_i over basal (unstimulated) levels. Values are means ± SE of 3 separate experiments and are significantly different from oxytocin only control (P < 0.01). TNFα did not have a modulatory effect on oxytocin-induced calcium response in these cells.