Table 1.

Clinico-pathological characteristics and TRAIL-R1 expression of patients with colorectal carcinoma

			High TRAIL-R1		Low TRAIL-R1		p value
	N	%	N	%	N	%
Total Number of Cases	387		331	85.5	56	14.5
Age
< = 50 years	126	32.6	110	87.3	16	12.7	0.4870
> 50 years	261	67.4	221	84.7	40	15.3
Gender
Male	193	49.9	167	86.5	26	13.5	0.5773
Female	194	50.1	164	84.5	30	15.5
Tumour Site
Left colon	324	83.7	276	85.2	48	14.8	0.6576
Right colon	63	16.3	55	87.3	8	12.7
Histological Type
Adenocarcinoma	334	86.3	291	87.1	43	12.9	0.0355
Mucinous Carcinoma	53	13.7	40	75.5	13	24.5
Tumour Stage
I	55	15.0	53	96.4	2	3.6	0.0251
II	126	34.2	105	83.3	21	16.7
III	141	38.3	121	85.8	20	14.2
IV	46	12.5	36	78.3	10	21.7
Differentiation
Well	33	8.5	30	90.9	3	9.1	0.0887
Moderate	284	73.4	247	87.0	37	13.0
Poor	70	18.1	54	77.1	16	22.9
KRAS Mutation
Present	75	28.3	67	89.3	8	10.7	0.7407
Absent	190	71.7	167	87.9	23	12.1
K-RAS 2A
High expression	155	46.7	150	96.8	5	3.2	< 0.0001
Low expression	177	53.3	142	80.2	35	19.8
Cleaved-Caspase 3
High expression	172	49.9	160	93.0	12	7.0	0.0011
Low expression	173	50.1	141	81.5	32	18.5
P27 (Nuc)
High expression	139	38.4	130	93.5	9	6.5	0.0024
Low expression	223	61.6	185	83.0	38	17.0
MSI-Molecular
MSI-H	67	18.7	56	83.6	11	16.4	0.4731
MSI-S/L	292	81.3	254	87.0	38	13.0
Overall Survival
5 Years				68.1		53.9	0.0124