Table 3.
TRAIL-R1 expression: Cox regression analysis for overall survival of patients with colorectal carcinoma
| UNIVARIATE | MULTIVARIATE | |||
|---|---|---|---|---|
| Clinical Parameters | Risk Ratio (95% CI) | p value | Risk Ratio (95% CI) | p value |
| Age: Above = 50 | 1.17 (0.80-1.74) | 0.4306 | 1.40 (0.86 - 2.33) | 0.1755 |
| Sex: Male | 1.10 (0.76-1.59) | 0.6084 | 1.18 (0.75 - 1.87) | 0.4589 |
| Stage: III-IV | 7.26 (4.34-13.03) | < 0.0001 | 6.56 (3.67 - 12.78) | < 0.0001 |
| Grade: Poorly differentiated | 1.41 (0.90-2.14) | 0.1307 | 3.61 (1.72 - 6.80) | 0.0014 |
| MSI status: MSI-L/S | 2.04 (1.14 - 4.05) | 0.0149 | 1.90 (0.95 - 4.37) | 0.0713 |
| Histology: Adenocarcinoma | 1.14 (0.67 - 2.10) | 0.6499 | 2.28 (0.93 - 5.43) | 0.0695 |
| TRAIL-R1: Low expression | 1.18 (1.11 - 2.83) | 0.0196 | 1.84 (1.10 - 3.02) | 0.0273 |
CI = confidence interval